There was a problem connecting to OneDrive Error Code: 0x8004e4d0
Where we see it happen is often where the UPN of the user has changed from when the Personal Site was created and for whatever reason something in the Microsoft back-end service has not processed the change correctly. On the face of it, nothing seems wrong. The OneDrive site owner is correct and the URL for the Personal OneDrive site is correct, and yet, the end-user cannot start the Desktop OneDrive application. Even going to the browser to connect to OneDrive also fails with an access denied error.